Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and. Amaç: İdiopatik trombositopenik purpura (ITP); trombositopenî, trombosit ömründe kısalma, plazmada anti-trombosit antikorların varlığı ve kemik iliğinde. Immune thrombocytopenic purpura (ITP) is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal.

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Immune thrombocytopenic purpura

The antibodies attach to the platelets. An ITP patient with an extremely low count is vulnerable to internal ppurpura caused by blunt abdominal traumaas might be experienced in purrpura motor vehicle crash. The bleeding manifestations of thrombocytopenia are described as mucocutaneous to distinguish them from coagulation disorders like hemophilia. Sudden and severe loss of blood from the digestive tract may occur. Basic Purpuura and Practice.

Nil Conflict of Interest: People with ITP should not take aspirin, ibuprofen, or warfarin, because these drugs interfere with platelet function or blood clotting, and bleeding may occur. Transfusion-associated graft versus host disease. Pediatric Blood and Cancer. For patient with active H. Dapsone also called diphenylsulfone, DDS, or avlosulfon is an anti-infective sulfone drug.

Cellular immune mechanisms in autoimmune thrombocytopenic purpura: Urea breath testing and stool antigen testing perform better than serology -based tests; moreover, serology may be false-positive after treatment with IVIG.

ABC of clinical haematology. Abstract Idiopathic thrombocytopenic purpura ITP is purprua as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. Nplate is an experimental treatment for stimulating platelet production. As most causes appear to be related to antibodies against platelets, it is also known as immune thrombocytopenic purpura. Diseases of the skin and appendages by morphology. Splenectomy is sometimes undertaken, as platelets targeted for destruction will often meet their fate in the spleen.


Not to be confused with autoimmune thrombotic thrombocytopenic purpura. Footnotes Source of Support: ITP is diagnosed by a low platelet count in a complete blood count a common blood test.

Archived from the original on Current guidelines recommend treatment only in cases of significant bleeding.

Go to the emergency room or call the local emergency number such as if severe bleeding occurs, or if other new symptoms develop. The patient was followed-up for 2 years and there was no re-occurence reported.

Immune thrombocytopenic purpura (ITP): MedlinePlus Medical Encyclopedia

Pertinent investigations were advised to the patient. Secondary causes could be leukemia, medications e. Review provided by VeriMed Healthcare Network. There is no specific treatment for ITP. From Wikipedia, the free encyclopedia.

The IgG autoantibodies are also thought to damage megakaryocytesthe precursor cells to platelets, although this is believed to contribute only slightly to the decrease in platelet numbers. This observation has led to the development of a class of ITP-targeted medications referred to as thrombopoietin receptor agonists.

In chronic refractory cases, where immune pathogenesis has been confirmed, [15] the off-label use of the vinca alkaloid [16] [17] [18] and chemotherapy purpuda vincristine may be attempted.

Эdiopatik Trombosltopenlk Purpura Tedavisinde Antt-D []

First, one has to make sure ppurpura there are no other blood abnormalities except for low platelet count and no physical signs except for signs of bleeding. Immune thrombocytopenia [1] ITP is a type of thrombocytopenic purpura defined as isolated low platelet count thrombocytopenia with normal bone marrow and the absence of other causes of thrombocytopenia.


Initial laboratory findings useful for predicting the diagnosis of idiopathic thrombocytopenic purpura. Older patients have more severe and rare bleeding manifestations, such as GI bleeding and possibly intracranial hemorrhage secondary to co-morbidities such as hypertension.

Immune idiopathic thrombocytopenic purpura: However, since the diagnosis depends on the exclusion of other causes of a low platelet count, additional investigations such as a bone marrow biopsy may be necessary in some cases.

Coagulopathies Vascular-related cutaneous conditions Idiopathic diseases Rare diseases. People with the disease have too few platelets in the blood. It should be limited in duration unless demonstrated that symptomatic thrombocytopenia persists.

Extraoral examination revealed petechial spots over the neck on right side [ Figure 1 ], petechial spots over the forearms, and petechial spots over the right arm [ Figure 2 ]. Immune thrombocytopenic purpura – From agony to agonist.

Fetal blood analysis to determine the platelet count is not generally performed as ITP-induced thrombocytopenia in the fetus is generally less severe than NAIT.